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A comparative evaluation between giving dexamethasone in aerosol form and magnesium sulphate in aerosol form and assessing whether it prevents post operative sore throat in patients undergoing surgeries under general anaesthesia

A Comparative study of efficacy of dexamethasone and MgSO4 preoperative nebulisation in reduction of postoperative sore throat following general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037147
Enrollment
80
Registered
2021-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nil: nil Control Intervention1: DEXAMETHASONE: DEXAMETHASONE IS A LONG ACTING SYNTHETIC DERIVATIVE OF CORTISOL. it is very helpful in relieving post.aerosol route Group A will receive n

Sponsors

GMC haldwani
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1- Patients belonging to ASA physical status â?? Grade I and II. 2- Surgeries under general anaesthesia following endotracheal intubation. 3- Duration of surgery less than 3 hours.

Exclusion criteria

Exclusion criteria: 1. Patient / guardian refusal for consent. 2. Patients having history of preoperative sore throat or recent upper airway infection,asthma ,chronic obstructive pulmonary disease 3. History of allergy to proposed/used drugs in the study. 4. Pregnant women. 5. Mallampati grade > II ( anticipated difficult airway ) 6. Patients on chronic medication(NSAID,STEROIDS) 7. Patients requiring more than one attempt at intubation or traumatic intubation. 8. Known smoker. 9. Time of intubation greater than 60 seconds.

Design outcomes

Secondary

MeasureTime frame
To grade the severity of POST between the two groups. To compare changes in hemodynamics and any related side-effects among groups.Timepoint: INTRAOPERATIVELY AT TIME 0 MIN 5 MIN 10 MIN AND 15 MIN AFTER INTUBATION RESPECTIVELY—

Primary

MeasureTime frame
To compare the effect of pre operative nebulisation of dexamethasone versus mgso4 on incidence of POSTTimepoint: sore throat will be assessed at 0 hr, 4 hr, 6 hr, 24 hr—

Countries

India

Contacts

Public ContactManoj singh kunwar

Government medical college ,haldwani ,nainital ,uttarakhand

drajayksinha@yahoo.co.in9897672301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026