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Impact of acute and chronic regular exercise on arterial stiffness and reflection measures in coronary artery disease patients

Impact of acute and chronic regular exercise on arterial stiffness and reflection measures in coronary artery disease patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037127
Enrollment
60
Registered
2021-10-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I700- Atherosclerosis of aorta

Interventions

Intervention1: 1.Aerobic exercises, 2. Resistance,3. Combined aerobic and resistance exercise, 4. No exercise: 1. 30-mins cycling at 60-90 % Heart rate maximum, 2. 30-mins Resistance training at 50-80

Sponsors

Jayoti Vidyapeeth Womens University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: the presence of CAD, which is defined as the patient having at least one of the following: angiographically documented stenosis >=50% in at least one major coronary artery; prior history of myocardial infarction (MI), percutaneous coronary intervention (PCI), or coronary artery bypass graft (CAGB) surgery; positive exercise stress test determined by a positive nuclear scan, or symptoms of chest discomfort accompanied by electrocardiographic (ECG) changes of > 1mm horizontal or down sloping ST segment depression.

Exclusion criteria

Exclusion criteria: non-cardiac surgical procedure within two months, MI or CABG within two months, PCI within one month, NYHA class II-IV symptoms of heart failure, documented valve stenosis, documented severe chronic obstructive pulmonary disease, symptomatic peripheral arterial disease, unstable angina, uncontrolled hypertension, uncontrolled atrial arrhythmia or ventricular dysrhythmia, insulin requiring diabetes mellitus, and any musculoskeletal abnormality that would limit exercise participation.

Design outcomes

Primary

MeasureTime frame
The primary objective of this research is to identify whether long term exercise can beneficially modify hemodynamic profile especially pulse wave velocity and augmentation index in subjects with Coronary artery diseaseTimepoint: 4 weeks and 8 weeks

Secondary

MeasureTime frame
This study will further investigate the mechanisms for changes in hemodynamic profile benefits to improve CVD risk for patients with CADTimepoint: 4 weeks and 8 weeks

Countries

India

Contacts

Public ContactDr Sandeep Singh

Jayoti Vidyapeeth Womenâ??s University

anchitgugnani19@gmail.com9351455030

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026