Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: DEXAMETHASONE: 6MG OD, 6MGBD, 12MG OD
Intervention2: NOT APPLICABLE: NOT APPLICABLE
Control Intervention1: NOT APPLICABLE: NOT APPLICABLE
Sponsors
Dr Sujith Vasireddy
Eligibility
Inclusion criteria
Inclusion criteria: 1)PCR confirmed COVID-19 infection 2)PaO2/FiO2 3)Positive pressure ventilation (non-invasive or invasive) or high flow nasal cannula (HFNC) higher than 45 L/min for less than 48 hours 4)Requiring ICU admission
Exclusion criteria
Exclusion criteria: 1)pregnancy; 2)Severe underlying disease, i.e. end stage of malignancy disease or end stage of pulmonary disease; 3)Underlying disease requiring corticosteroids; Contraindication for corticosteroids 4)Diseases causing an immunocompromised state, i.e AIDS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALL CAUSE MORTALITYTimepoint: Till discharge from the hospital | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac complicationsTimepoint: After administration of steroid till discharge from the hospital;Development of ARDSTimepoint: After administration of steroid till discharge from the hospital;Length of hospital StayTimepoint: till discharge from the hospital;New requirement of ventilatory supportTimepoint: After administration of steroid till discharge from the hospital;Number of days of oxygen supportTimepoint: till discharge from the hospital;PneumoniaTimepoint: After administration of steroid till discharge from the hospital;Renal complicationsTimepoint: After administration of steroid till discharge from the hospital;SepsisTimepoint: After administration of steroid till discharge from the hospital;Steroid induced complicationTimepoint: After administration of steroid till discharge from the hospital;Transfer to ICUTimepoint: After administration of steroid till discharge from the hospital;Vascular ComplicationsTimepoint: After administration of steroid till discharge from the hospital | — |
Countries
India
Contacts
Public ContactSujith Vasireddy
Kasturba Medical College, Manipal
Outcome results
None listed