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To compare the degree of patient comfort during awake fiberoptic intubation using dexmedetomidine with lignocaine versus plain lignocaine

A comparative study of Dexmedetomidine with Lignocaine versus plain Lignocaine nebulization for awake fiber-optic intubation: An Observational Cross-sectional study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037069
Enrollment
96
Registered
2021-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fiberoptic Intubation: Patients will receive nebulization with Dexmedetomidine 1mcg/kg body weight + 4ml 4% plain lignocaine Control Intervention1: Awake fiberoptic intubation: Patients

Sponsors

Himalayan Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with anticipated difficult intubation. 2. Patients aged between 18 - 65 years of both genders who upon being explained the procedure are willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients who are uncooperative to awake fiberoptic intubation. 2. Patients allergic to lignocaine, xylometazoline, phenylephrine or glycopyrrolate. 3. Patients with uncontrolled diabetes mellitus, hypertension or heart block. 4. Patients who are on beta-blockers. 5. Patients with a history of bleeding diathesis. 6. Patients with bradyarrhythmia. 7. Asthmatic patients.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of dexmedetomidine nebulization and plain lignocaine so as to achieve successful airway assessment to assess the quality of airway anaesthesia to assess patient comfort score on basis of number of attempts of cough,gag reflex and hemodynamic stability. Time Points : 4weeks, 8weeksTimepoint: To compare the efficacy of dexmedetomidine nebulization and plain lignocaine so as to achieve successful airway assessment to assess the quality of airway anaesthesia to assess patient comfort score on basis of number of attempts of cough,gag reflex and hemodynamic stability. Time Points : 4weeks, 8weeks—

Secondary

MeasureTime frame
To compare patient sedation in both groups and to assess the complication if any occurs during awake fiber-optic intubation.Timepoint: To compare patient sedation by using Ramsay Sedation Score (1 to 6 Scale). Estimated i.e. at baseline, 4 weeks and 8 weeks—

Countries

India

Contacts

Public ContactDr Neeru Yadav

Himalayan Institute of Medical Sciences, Swami Rama Himalayan University

yadavneeru5847@gmail.com9149022493

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026