FindTrial
Sign In

Effect of Hyaluronic Acid on success of Intrauterine Insemination Treatment

Effect of Intrauterine Instillation of Hyaluronic Acid Rich Media on Clinical Outcomes of Intrauterine Insemination Treatment: A Randomized Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037064
Enrollment
30
Registered
2021-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Instillation of Hylauronic acid after IUI: 0.4 ml INSTILLATION OF HYLAURONIC ACID VIA IUI CATHETER AT INTERNAL OS Control Intervention1: NORMAL IUI procedure without adding HYLAURONIC A

Sponsors

All India Institute of Medical Sciences Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Couples unable to conceive after having regular, unprotected sexual intercourse for >12 months. 2. BMI 3. Husband Semen Analysis within normal references ranges as per WHO 2010 criteria, within last 6 months. 4. Tubal patency documented by HSG/Laparoscopy. 5 Normal Transvaginal ultrasound to exclude any pelvic structural pathology. 6.Genital TB infection ruled out by TB-PCR /BACTEC. 7. Patient consenting to undergo ovulation induction and Intra-uterine insemination treatment

Exclusion criteria

Exclusion criteria: Patients not giving consent or not willing to follow up.

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of intrauterine instillation of hyaluronic acid enriched media on clinical pregnancy rate in intrauterine insemination treatment.Timepoint: 18 months for recruitment and 6 months for follow up and analysis—

Secondary

MeasureTime frame
Secondary Objectives- 1.To assess the effect of intrauterine instillation of hyaluronic acid enriched media on biochemical and ongoing pregnancy rate up to 20 weeks in intrauterine insemination treatment. 2.To the effect of intrauterine instillation of hyaluronic acid enriched media on miscarriage rate in intrauterine insemination treatment. 3.To estimate patient discomfort and pain following intrauterine instillation using standard pain scale. Timepoint: 18 months for recruitment and 6 months for follow up and analysis—

Countries

India

Contacts

Public ContactNavdeep Kaur Ghuman

AIIMS Jodhpur

drnavdeepghuman@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 6, 2026