None listed
Conditions
Interventions
Intervention1: Autologous Conditioned Serum (ACS): Autologous conditioned serum (ACS), is a novel, injectable material derived from the patientâ??s own blood. ACS preparations are a source of anti-inf
Sponsors
Dr Chandini Ravikumar
Eligibility
Inclusion criteria
Inclusion criteria: Healthy patients aged 20-50 years, diagnosed with TMJ internal derangement according to Wilkes classification (stage 2-4), and who are not under NSAIDs medication are included in the study.
Exclusion criteria
Exclusion criteria: Patients with rheumatic disease, any surgical intervention of the TMJ, infection, diabetes, severe cardiovascular disease, coagulopathy, anticoagulant therapy and pregnancy are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical parameters assessed are TMJ pain, clicking sounds, mouth opening, jaw deviation, functional limitation and masticatory efficiency. A positive outcome, with 90% improvement in clinical condition would be expected in this prospective study.Timepoint: The parameters are assessed pre-operatively, post-operatively immediate, 2 weeks, 1 month and 2 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiological parameters to be assessed are joint effusion, disc displacement, disc non-recapture, disc degenerative changes, abnormal condyle translation and condyle arthritis.Timepoint: MRI parameters are assessed using TMJ internal derangement score (TIDS score 0 to 12). MRI will be taken pre-operatively and post-operatively after 2 months. | — |
Countries
India
Contacts
Public ContactChandini Ravkumar
SRM Dental College and Hospital
Outcome results
None listed