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Measurement of Optic nerve swelling in patients undergoing robot assissted laparoscopic prostatectomy with or without mannitol

Optic nerve sheath diameter in patients undergoing robot assissted laparoscopic prostatectomy with or without mannitol- a randomised controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037021
Enrollment
60
Registered
2021-10-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N423- Dysplasia of prostate Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Mannitol: Mannitol(20%) is given in a iv dose of 2ml/kg over a duration of 30 mins once just after the positioning of the patient Control Intervention1: Normal Saline: Normal Saline is

Sponsors

Sir gangaram hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age - 40-79 yrs 2 ASA Grade I-II patients 3 BMI - 18.5 - 27.5 kg/m2

Exclusion criteria

Exclusion criteria: 1 Refusal to participate in study. 2 History of cerebrovascular accident. 3 Any cardiac or pulmonary disease. 4 History of ocular or intracranial surgery. 5 History of anaphylaxis to mannitol. 6 Combined with any other surgery

Design outcomes

Primary

MeasureTime frame
Optic nerve sheath diameter will be recording in patients undergoing Robot asissted laparoscopic prostatectomy in Steep Trendelenberg position at different time intervals.Timepoint: At induction of anesthesia (T0); after STP was attained(T1); iv saline or mannitol will be started and observation recorded ;30 min after STP (T2); 1hr after STP (T3); and then every hr till extubation and lastly at extubation..—

Secondary

MeasureTime frame
To compare in patients undergoing robot assisted laparoscopic prostatectomy in Trendelenberg position with or without â??mannitolâ?? administration at different time intervals and at extubation: 1. Depth of anesthesia using bispectral index 2. Recovery from anesthesia using time to extubate, recovery time, time to respond to verbal command, OASS(overt Agitation Severity Scale), MMSE(Mini Mental Status Examination).Timepoint: Bispectral Index - At induction of anesthesia (T0); after STP was attained(T1); 30 min after STP (T2); 1hr STP (T3); and then every hr till extubation and lastly at extubation. At extubation â?? extubation time, recovery time, time to response to verbal command, OASS After extubation- MMSE—

Countries

India

Contacts

Public ContactRiya Khandelwal

Sir Gangaram hospital

sshikha18@gmail.com9810382283

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026