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A clinical trial to compare the effect of a non invasive breathing support modality, high flow nasal cannula against conventional oxygen delivery equipments in preventing patients going back to ventilator after taking them off from it.

Comparison of the effectiveness of High-flow nasal cannula oxygen therapy versus Conventional oxygen therapy in preventing reintubation after extubation in children admitted to Pediatric Intensive Care Unit in a tertiary care hospital : an open label, randomised control trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036985
Enrollment
102
Registered
2021-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J219- Acute bronchiolitis, unspecified Health Condition 2: G049- Encephalitis, myelitis and encephalomyelitis, unspecified Health Condition 3: Q208- Other congenital malformations ofcardiac chambers and connections Health Condition 4: I518- Other ill-defined heart diseases Health Condition 5: D618- Other specified aplastic anemias and other bone marrow failure syndromes

Interventions

Intervention1: High Flow Nasal Cannula: Post extubation patients will be randomised and allocated to two groups. One group will be provided with high flow nasal cannula and monitored for failure of ex

Sponsors

Narayana Hrudalaya Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients in PICU who will undergo extubation after more than 12 hours of mechanical ventilation.

Exclusion criteria

Exclusion criteria: Caregivers of patients not giving consent for participating in the study. Randomization not done due to physician choice of post extubation support. Diaphragmatic paralysis. Presence of a tracheostomy tube.

Design outcomes

Primary

MeasureTime frame
Reintubation(going back on ventilator support)Timepoint: 48hours. Reintubation(going back on ventilator support) within first 48hours after removal from ventilator.—

Secondary

MeasureTime frame
Change in vital hemodynamic parameters and work of breathing.Timepoint: 48hours—

Countries

India

Contacts

Public ContactPriyabrata Panda

Narayana Hrudalaya, Bangalore

docsagar2002@yahoo.co.in9972703780

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026