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A study to compare antibacterial efficacy of clindamycin modified triple antibiotic paste with calcium hydroxide in root canals of deciduous molars.

Comparative study on CFU/ml between clindamycin modified triple antibiotic paste and calcium hydroxide as intracanal medicaments in primary molars- a randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036939
Enrollment
26
Registered
2021-09-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K046- Periapical abscess with sinus Health Condition 2: K047- Periapical abscess without sinus

Interventions

Intervention1: Triple antibiotic paste: 250 mg of ciprofloxacin, 250 mg of metronidazole and 150 mg of clindamycin mixed with propylene glycol, placed in root canals for 7 days Control Intervention1:

Sponsors

Malavika Rajan
Lead Sponsor
Shivani B
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Teeth with one or more of the following criteria requiring pulpectomy will be included. 1 Caries affected primary molars with intraoral and/or extraoral swelling or intraoral draining sinus tract. 2 Primary molars with deep caries lesions and associated inter-radicular and/or periapical radiolucencies. 3 Caries-affected primary molars with abnormal mobility due to periapical pathosis, but not associated with normal exfoliation. 4 Caries-affected primary molars with internal root resorption involving the cervical 1/3 of the root or external resorption (not physiologic resorption) involving less than 1/3 of the root length.

Exclusion criteria

Exclusion criteria: 1 Previous history of allergy to the antibiotics.

Design outcomes

Primary

MeasureTime frame
Antimicrobial efficacy in terms of aerobic microbial count, anaerobic microbial count and Enterococcus faecalis countTimepoint: 1 week

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactShivani B

Bapuji Dental College and Hospital

drshivani.bdch@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026