Health Condition 1: I10- Essential (primary) hypertension
Conditions
Interventions
Intervention1: 150 MG ASPIRIN: PREGNANT WOMEN WHO WILL COME UNDER HIGH RISK FOR PREECLAMPSIA WITH FMF -ECLAMPSIA CALCULATOR WILL BE STARTED AND AFTER RANDOMIZATION WILL BE STARTED WITH 150 MG ASPIRIN
Sponsors
AIIMS RAIPUR
Eligibility
Inclusion criteria
Inclusion criteria: 1.Maternal age >= 18y 2.Singleton pregnancy 3.Women at high risk of preeclampsia by means of first trimester screening at 11-14 weeks gestational age (crown-rump length of 45â??84 mm) : diagnosed by FETAL MEDICINE FOUNDATION(FMF) ECLAMPSIA CALCULATOR
Exclusion criteria
Exclusion criteria: 1. Contraindication to use of Aspirin Active peptic ulcer disease Bleeding disorder Chronic Kidney Disease Thrombocytopenia( Known allergy or hypersensitivity to aspirin . 2. Active treatment with heparin or aspirin before recruitment 3. Known Foetal malformation, Anomaly, Aneuploidy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Incidence of PE before 37 weeks in the two interventional groups . 2. The severity of PE, FGR and the neonatal outcome between the two groups Timepoint: OUTCOME WILL BE ASSESSED AT DAY 2 OF DELIVERY | — |
Secondary
| Measure | Time frame |
|---|---|
| SIDE EFFECTS ASPIRIN ALLERGY e.g. Uticaria Anaphylaxis GI BLEEDING GENITOURINARY BLEEDING/ BLEEDING PV Any other (specify)Timepoint: AT EACH ANTENATAL VISIT THAT IS MONTHLY AFTER STARTING OF MEDICATION ,UPTO 28 WEEKS.TWICE A MONTH FROM 28 WEEKS POG TILL 36 MONTH AND PATIENT WILL ALSO BE ASKED TO REPORT IMMEDIATELY ANYTIME ANY SIDE EFFECTS OCCUR. THEY WILL BE ASKED TO REPOERT ANY SIDE EFFECT AT ANYTIME SINCE THE START OF MEDICATION,IF ANY OCCURS | — |
Countries
India
Contacts
Public ContactDrChandrashekhar Shrivastava
AIIMS RAIPUR
Outcome results
None listed