Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Intervention1: Indo Mediterrenean diet: Indian version of Mediterranean diet will be given to NAFLD children for 180 days
Control Intervention1: Calorie restricted diet: Diet restricted in calories (a
Sponsors
Institute of liver and biliary sciences
Eligibility
Inclusion criteria
Inclusion criteria: • Age 8-18 years • BMI > 85th centile • USG s/o Fatty Liver • Biopsy proven NAFLD
Exclusion criteria
Exclusion criteria: • Other Liver diseases such as Viral hepatitis (Hep B and C), Autoimmune hepatitis, Wilson disease • Liver Biopsy not done • Refused Consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Primary outcome measure will be a composite end point defined by decrease in CAP and ALT values by 10% from baseline and decrease in PNFI score to less than 3Timepoint: 180 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Lipid Profile (Time frame : Change in Cholesterol, triglycerides of atleast 10% from baseline at 180 days) Lipid profile will be measured in a fasting state Timepoint: 180 days;Weight (Time frame : Change in Weight of atleast 7% from baseline at 180 days) Weight will be recorded at the baseline and at the completion of diet intervention Timepoint: 180 days | — |
Countries
India
Contacts
Public ContactAniket Deshmukh
Institute of Liver and biliary sciences, Delhi
Outcome results
None listed