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Evaluation of silver diamine fluoride as a cleaning agent against primary teeth root canal

Evaluation of anti-microbial efficacy of 3.8% silver diamine fluoride as root canal irrigant against Enterococcus faecalis in primary teeth: An in vivo study.

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036881
Enrollment
60
Registered
2021-09-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp Health Condition 2: R52- Pain, unspecified

Interventions

Intervention1: Silver diamine fluoride: 0.5 ml of 3.8% silver diamine fluoride for 5 seconds will be used as an root canal irrigant. Silver diamine fluoride has an antimicrobial property and is used a

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Primary teeth of maxillary or mandibular, anterior/posterior containing at least one necrotic pulp canal, abscess, or sinus tract. Presence of radiolucent area in furcation or periapical region. At least two-thirds of the root remains. Sufficient tooth structure to support a rubber dam.

Exclusion criteria

Exclusion criteria: Patients who had received antibiotics up to 2 weeks prior to the sampling or having any systemic compromise. Patients who had non-restorable teeth, perforated pulpal floor, excessive mobility, or pathological root resorption.

Design outcomes

Primary

MeasureTime frame
Silver diamine fluoride may have better antimicrobial property than Chlorhexidine gluconate as an irrigant in primary teeth.Timepoint: 1 year

Secondary

MeasureTime frame
Chlorhexidine gluconate may have better antimicrobial property than Silver diamine fluoride as an irrigant in primary teeth.Timepoint: 1 year

Countries

India

Contacts

Public ContactVeena Arali

GSL Dental College and Hospital

gslpedo@gmail.com7760748787

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026