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Comparison of effect of preoperative nebulised dexamethasone and ketamine in reducing post operative sore throat in patients under GA

Comparison of Effectiveness of Preoperative nebulised Dexamethasone versus Ketamine on attenuating occurance and severity of Post operative sore throat following Endotracheal intubation in patients under general anaesthesiaâ?? : Prospective Double blind Randomized control Trial - CDKG

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036867
Enrollment
60
Registered
2021-09-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: nebulisation: comparing the efficacy of reducing postoperative sore throat by giving preoperative nebulisation with ketamine 50 mg with 4 ml normal saline and that with dexamethasone 8

Sponsors

Prachi Shah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 And 2 Patient undergoing Surgery under General Anaesthesia following Endotracheal intubation

Exclusion criteria

Exclusion criteria: Patient with preoperative sore throat,upper respiratory tract infection,COPD ,bronchial asthma. Patient undergoing oral surgeries,head & neck sugeries Allergy to any one or both studyong drugs current use of corticosteroids or NSAIDS immunocompromised patient /long term use of immunosuppressants patient with risk factor for post operative aspiration.ex.obese and diabetec patients >1 attempt of intubation Mallampatti grade >2 patient with preoperative cough,preoperative hoarseness of voice

Design outcomes

Primary

MeasureTime frame
To compare the occurance and severity of post operative sore throat after preoperativene nebulisation with ketamine and dexamethasone in patient undergoing surgery under general anaesthesia following endotracheal intubationTimepoint: To compare the occurance and severity of post operative sore throat after preoperative nebulisation with ketamine and dexamethasone in patient undergoing surgery under general anaesthesia following endotracheal intubation At 0 , 2 ,4,6,12 & 24 hrs

Secondary

MeasureTime frame
to compare change in hemodynamic parameters such as pulse,BP between both groups to compare frequency of postoperative nausea & vomiting,cough,hoarseness of voice betweeen both the groups.Timepoint: 24 hrs postoperative group

Countries

India

Contacts

Public ContactDr shilpa Doshi

Government Medical college,Bhvnagar

drshilpadoshi@yahoo.in9428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026