The efficacy of tranexamic acid which is a drug that promotes clotting of blood, in preventing blood loss in patients undergoing surgeries in and around hip joint

Evaluation of efficacy of tranexamic acid on blood loss in periarticular hip surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/09/036855

Enrollment

100

Registered

2021-09-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V00-Y99- External causes of morbidity

Interventions

Intervention1: Tranexamic acid: Tablets containing 1950mg of tranexamic acid given 2 hours prior to incision for surgery and 2g of injection tranexamic acid diluted in 20ml normal saline given through

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring major periarticular hip surgeries

Exclusion criteria

Exclusion criteria: 1.Psychiatric patients 2.Any abnormal bleeding disorder like hemophilias, deranged international normalized ratio 3.Any previous history of adverse reaction or allergy to tranexamic acid 4.Congenital or acquired coagulopathy 5.Recent history of thrombo-embolic episode 6.Fracture neck of femur requiring closed reduction internal fixation with cannulated cancellous screws 7.Implant removal procedure

Design outcomes

Primary

Measure	Time frame
To assess the efficacy of Tranexamic acid in reducing intra and post-operative blood loss volume(during first 48 hours) in patients undergoing periarticular hip surgeriesTimepoint: To assess the efficacy of Tranexamic acid in reducing intra and post-operative blood loss volume(during first 48 hours) in patients undergoing periarticular hip surgeries	—

Secondary

Measure	Time frame
To assess the reduction of requirement of blood transfusion both inra-operative and during first 48 hours post surgery. To assess any thromboembolic eventsTimepoint: first 48 hours post surgery 3 months post surgery	—

Countries

India

Contacts

Public ContactMayukh Mukherjee

Pt BD Sharma PGIMS Rohtak

drmayukh780@gmail.com8820399862

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026