Health Condition 1: I249- Acute ischemic heart disease, unspecified
Conditions
Interventions
None listed
Sponsors
Society for Coronary Imaging and Physiology SCIP
Eligibility
Inclusion criteria
Inclusion criteria: Patients who are undergoing IVUS guided PCI for diagnosis of 1) ST elevation myocardial infarction (STEMI): Defined as chest pain with > 1mm STE in 2 contigous leads except V2 & V3. In V2 & V3, STE of > 2mm in males & > 1.5mm in females 2) Non ST elevation myocardial infarction (NSTEMI): Defined as chest pain with ECG changes consistent with new ischemia ( ST depression , T inversions ) with troponin elevation 3. Unstable angina: Defined as chest pain at rest or minimal effort with or without ECG changes and no biomarker elevation
Exclusion criteria
Exclusion criteria: 1) cardiogenic shock - as defined by SBP 2) Hemodynamic instability - as defined by recurrent VT / acute pulmonary oedema / need for ventilator support / mechanical cardiac support - or any instance where operator feels performing imaging is not possible due to clinical instability 3) Stent thrombosis / restenosis - any stent failure related vessel 4) Graft interventions 5) Inability to perform either pre or post IVUS images 6) Mechanical complications 7) Planned CABG in next 30 days 8) Severe comorbidities which restrict life span to 9) Presenting eGFR 10) Age 90 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. TIMI flow 2 at end of procedure 2. Target lesion revascularisation at any time point ( inhospital, 30 days, 6months)Timepoint: 1. TIMI flow 2 at end of procedure 2. Target lesion revascularisation at any time point ( inhospital, 30 days, 6months) | — |
Secondary
| Measure | Time frame |
|---|---|
| Echo derived LV function ( ejection fraction)Timepoint: end of procedure, at 30 days and 6 months;Incidence of adverse eventsTimepoint: end of procedure, at 30 days and 6 months;Incidence of cardiac death, MI, target lesion revascularisation, any unplanned revascularisation and LV function (extended followup)Timepoint: at 1 year;IVUS analysis of plaque morphologyTimepoint: inhospital, 30 days & 6 months;MACE (cardiac death, MI and need for repeat target lesion revascularisation ( TLR), any unplanned revascualrisation)Timepoint: inhospital, 30 days & 6 months | — |
Countries
India
Contacts
Public ContactDr Sajan Narayanan MD DM
Little Flower Hospital and Research Institute
Outcome results
None listed