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Trial of HHHFNC (Heated Humidified High flow nasal cannula) versus standard oxygen therapy in children with low oxygen saturation due to respiratory disease.

Multicentric randomized trial of Heated Humidified High Flow Nasal Cannula (HHHFNC) versus standard Oxygen therapy in Hypoxemic Respiratory failure in Children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036844
Enrollment
70
Registered
2021-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: HHHFNC: Use of HHHFNC in Hypoxemic Respiratory failure in children Control Intervention1: Standard oxygen therapy: Standard oxygen therapy in form of nasal prongs and face mask in Hypox

Sponsors

DGAFMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children with hypoxemic respiratory failure

Exclusion criteria

Exclusion criteria: Children requiring intubation , cyanotic congenital heart disease, presence of air leak at admission, nasal deformities/ injury, refusal by parents

Design outcomes

Primary

MeasureTime frame
Reduction in rate of mechanical ventilation, Reduction in respiratory score, SpO2/PaO2 and PaCO2 Timepoint: 1 hourly for the first 6 hours, 4 hourly for next 12 hours, 6 hurly for next 54 hours, total of 72 hours or early if improved—

Secondary

MeasureTime frame
Length of PICU stay, Complications like nasal injuries and pneumothoraxTimepoint: 1 hourly for the first 6 hours, 4 hourly for next 12 hours, 6 hurly for next 54 hours, total of 72 hours or early if improved—

Countries

India

Contacts

Public ContactHitesh Daryani

INHS Asvini

daryani.hitesh88@gmail.com9975288797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026