FindTrial
Sign In

Comparison of Desflurane and Isoflurane

A RCT to compare the emergence response of patients undergoing general anesthesia with desfluane or isoflurane for elective ENT surgeries.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036834
Enrollment
60
Registered
2021-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: DESFLURANE: IN GROUP 1 , PATIENTS WILL BR GIVEN GENERAL ANESTHESIA WITH DESFLURANETILL THE END OF PROCEDURE THROUGH INHALATIONAL ROUTE IN A DOSE TO ACHIEVE MAC OF 1.2. Control Intervent

Sponsors

Government Institute of Medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ALL ASA I & II PATIENTS FOR ELECTIVE ENT SURGERIES UNDER GENERAL ANESTHESIA

Exclusion criteria

Exclusion criteria: ASA III & IV PATIENTS, EMERGENCY SURGERIES, PATIENTS WITH HEPATIC, RENAL, NEUROLOGICAL DISEASE, ALCOHOL & DRUG ABUSE, PREGNANCY.

Design outcomes

Primary

MeasureTime frame
EMERGENCE TIME AS NOTED BY TIME TO EYE OPENINGTimepoint: FROM END OF SURGERY, 1, 2,3 ,4,5,6,7, 8, 9, 10 MIN—

Secondary

MeasureTime frame
TIME TO EXTUBATION TIME AT WHICH PATIENT FOLLOWS MOTOR COMMANDS: PROTRUSION OF TONGUE, SUSTAINED HEAD LIFT 5s. TIME OF ABILITY TO STATE NAME & ADDRESS. EFFECT ON HEART RATE, MEAN ARTERIAL PRESSURE, END TIDAL CO2 & END TIDAL AGENT CONCENTRATION. INTRAOPERATIVE OPIOID CONSUMPTION & RELAXANT CONSUMPTION. TIME TO DISCHARGE FROM PACU COST EFFECTIVENESS.Timepoint: BASELINE, 2 MIN, 4 MIN , 6 MIN, 8 MIN, 10 MIN, 12, 14,16, 18, 20 MIN, 30, 40 50, 60, 70 MIN—

Countries

India

Contacts

Public ContactDr Nazia Nazir

Government Institute of Medical sciences

nazunazir@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026