Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Mid treatment replanning: Patients on IMRT/Chemo-IMRT are rescanned after 20th fraction and replanned and new plan is executed at 22nd fraction
Control Intervention1: Not applicable:
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with histologically proven Squamous Cell Carcinoma of head and neck region 2. Age 3. Primary tumour sites in oral cavity, oropharynx, hypopharynx and larynx. 4.Stage III-IVB by AJCC Cancer Staging Manual Eight Edition, 2018 5.Eastern Cooperative Oncology Group (ECOG) performance status 6.All patients fit for chemo-radiation/Radiation Therapy
Exclusion criteria
Exclusion criteria: 1. Patients with resection of the primary tumour or recurrent disease 2. Patients with distant metastasis 3. Patients who have received prior NACT or surgery 4. Patients who have received prior radiation therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the quality of life in Locally advanced Head and Neck cancer patients undergoing IMRT/Chemo-IMRT with mid treatment adaptive replanningTimepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To asses acute toxicity during 6 weeks in patients of Locally advanced Head and Neck cancers undergoing IMRT with mid treatment adaptive replanning 2. To assess the incidence of xerostomia at 6 months in patients of Locally advanced Head and Neck cancers undergoing IMRT with mid treatment adaptive replanning Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Sweety Gupta
AIIMS Rishikesh
Outcome results
None listed