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Comparison of two procedures for regeneration of dental pulp in teeth with open apex

Comparative evaluation of efficacy of regenerative endodontic procedures in teeth with open apices using PRF and induced blood clotting for periapical healing- A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036778
Enrollment
32
Registered
2021-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Regenerative Procedure: The clinical study will be performed at the Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College, Wardha, Maharashtra. After taking

Sponsors

Datta Meghe Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Will be having necrotic single-rooted maxillary anterior tooth with mature root. -The selected patients will be without known allergic reactions to any of the antibiotics used or systemic disease.

Exclusion criteria

Exclusion criteria: -Pregnant females -Patients with generalized chronic periodontitis -Patients having non-restorable teeth -Teeth where pulp space is needed for post or teeth with previous root canal treatment -Teeth with developmental anomalies -Teeth with external and internal resorption

Design outcomes

Primary

MeasureTime frame
Periapical healingTimepoint: T0 (3 months), T1(6 months), T2 (1 year), T3(3years) and T4(5years)—

Secondary

MeasureTime frame
Apical closure,Root lengthening and dentinal wall thickeningTimepoint: T0 (3 months), T1(6 months), T2 (1 year), T3(3years) and T4(5years)—

Countries

India

Contacts

Public ContactPradnya Nikhade

Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences

drpradnyanikhade@gmail.com7447463783

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026