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Lung Ultrasound Score and its predictability for need of surfactant and grade of severity of respiratory distress syndrome in premature neonates -a Cohort study Study

Point of Care Lung Ultrasound Score (POCUS) to predict the severity of respiratory distress syndrome and surfactant need in preterm neonates - Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/09/036770
Enrollment
82
Registered
2021-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P220- Respiratory distress syndrome of newborn

Interventions

Intervention1: NIL: NIL

Sponsors

Manish Swami
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All babies <=32 weeks/ <=1250gms with respiratory distress within first 2 hours of life irrespective of type respiratory support or requirement of resuscitation needed at birth.

Exclusion criteria

Exclusion criteria: 1.Neonates with hemodynamic instabilities (severe sepsis/ refractory shock). 2.Neonates with antenatally detected intrathoracic malformations including congenital heart defects 3.Neonates with other associated respiratory morbidities (air-leaks, MAS, pulmonary haemorrhage) 4.Babies admitted to the NICU after administration of surfactant in the delivery room 5.Consent/ Assent not given by parents

Design outcomes

Primary

MeasureTime frame
1.POCUS Lung score will be assessed in 6 predefined areas of lung fields, Within 2 hours after birth and before administration of surfactant. 2.Requirement of surfactant- when baby on Nasal Continuous Positive Airway Pressure (NCPAP) 5 cm of water with FIO2 requirement â?¥0.30 (â?¤26 weeks), or â?¥0.40 (26 weeks) with target SpO2 of 91% â?? 95% (after 10 min of life) Timepoint: 1.POCUS Lung score will be assessed in 6 predefined areas of lung fields, Within 2 hours after birth and before administration of surfactant. 2.Requirement of surfactant- when baby on Nasal Continuous Positive Airway Pressure (NCPAP) 5 cm of water with FIO2 requirement â?¥0.30 (â?¤26 weeks), or â?¥0.40 (26 weeks) with target SpO2 of 91% â?? 95% (after 10 min of life)—

Secondary

MeasureTime frame
1.Oxygenation status-Oxygenation Index (OI),a/A ratio, S/F ratio,PaO2. 2.Nasal CPAP failure and need for invasive mechanical ventilation within the first 72 hours after birth. 3.Severity of RDS on Chest Xray. 4.Severity of RDS based on clinical parameters (Silverman-Andersen score). Timepoint: 1.Oxygenation status-Oxygenation Index (OI),a/A ratio, S/F ratio,PaO2- with in 30 mins of lung ultrasound 2.Nasal CPAP failure and need for invasive mechanical ventilation within the first 72 hours after birth. 3.Severity of RDS on Chest Xray-with in 30 mins of lung ultrasound 4.Severity of RDS based on clinical parameters (Silverman-Andersen score)-with in 30 mins of lung ultrasound—

Countries

India

Contacts

Public ContactManish Swami

AIIMS,Bhubaneswar

neonat_tapas@aiimsbhubaneswar.edu.in9438884114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026