Health Condition 1: V00-Y99- External causes of morbidity Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical
Conditions
Interventions
Intervention1: Pre-operative nebulisation with 1µg/kg of dexmedetomidine: Patients will be nebulised for 10 minutes with 5 ml of solution containing 1µg/kg of dexmedetomidine in 0.9% NaCl, 10 minut
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: • Age more than 18 years • ASA I & II patients undergoing surgery under general anaesthesia • Patient with Mallampati class 1 or 2
Exclusion criteria
Exclusion criteria: • Pregnant females • Patient with unstable haemodynamics • Predicted airway difficulty • ASA III & IV patients • Known allergy to dexmedetomidine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢ To find most effective dose of nebulised dexmedetomidine with minimal side effect in blunting haemodynamic response to laryngoscopy and intubation by comparing HR, SBP, DBP and MAP at pre-induction, pre-intubation, after-intubation and upto 10 minutes post intubation.Timepoint: BASELINE, after 5 mins i.e during nebulisation, after 10 mins i.e post nebulusiation, Pre-induction, Pre-intubation, Post intubation and then after every one min till BP and HR comes normal. | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ To compare effect of 1 & 2 μg/kg nebulised dexmedetomidine on reduction of induction dose of propofol. â?¢ To compare incidence and magnitude of complication associated with use of 1 & 2 μg/kg nebulised dexmedetomidine. Timepoint: -During induction. -Complication noticed throughout study | — |
Countries
India
Contacts
Public ContactDr Ashima Mahajan
Dayanand Medical College and Hospital, Ludhiana. 141001 Punjab India
Outcome results
None listed