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To study the effects of inhalational and iv dexmedetomidine during intubation in awake patients

Comparative evaluation of nebulised versus intravenous dexmedetomidine on intubating conditions during awake fiberoptic nasotracheal intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036731
Enrollment
46
Registered
2021-09-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: NEBULISED DEXMEDETOMIDINE: Group ND: Will receive nebulisation with dexmedetomidine 1 mcg/kg in 4 ml of 4 % lidocaine and 10 ml NS intravenously over 10 mins. Control Intervention1: I

Sponsors

Department of Anaesthesiology and Intensive care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II

Exclusion criteria

Exclusion criteria: 1. KNOWN ALCOHOLIC OR DRUG ABUSERS 2.ALLERGY TO THE DRUGS INVOLVED IN THE STUDY 3. BRADYCARDIA , ANY TYPE OF ATRIOVENTRICULAR BLOCK 4. ANY CONTRAINDICATION FOR NASAL INTUBATION LIKE THROMBOCYTOPENIA AND COAGULOPATHIES 5. FULL STOMACH PATIENTS 6. RECENT UPPER RESPIRATORY TRACT INFECTIONS 7. ANTICIPATED DIFFICULT AIRWAY 8. PREGNANCY

Design outcomes

Primary

MeasureTime frame
COUGH SCORETimepoint: at 1 time point - during the passage of the ETT into the trachea

Secondary

MeasureTime frame
HEMODYNAMIC PARAMETERS:( MAP, HR and spo2)Timepoint: at baseline, after infusion of study drug and every 1 min after intubation for 5 mins;PATIENT SATISFACTION SCORETimepoint: at patient follow up after 24 hours;PHARYNGO-LARYNGEAL MORBIDITTYTimepoint: AT PATIENT FOLLOW UP AFTER 24 HOURS;POST INTUBATION SCORETimepoint: AFTER PROPER PLACEMENT OF THE ETT IN THE TRACHEA;RECALL OF THE PROCEDURETimepoint: at patient follow up after 24 hours;REQUIREMENT OF ADDITIONAL BOLUSES OF 1ML OF 2% LIGNOCAINE BY SPRAY AS YOU GO TECHNIQUETimepoint: DURING AWAKE FIBEROPTIC NASOTRACHEAL INTUBATION;SEDATION SCORETimepoint: AFTER ADMINISTRATION OF THE STUDY DRUG

Countries

India

Contacts

Public ContactAnju R Bhalotra

Maulana Azad Medical College

drakgk@yahoo.co.in9968604219

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026