Health Condition 1: C61- Malignant neoplasm of prostate Health Condition 2: C61- Malignant neoplasm of prostate
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Body Mass Index Less Than 30 American Society of Anaesthesiologists Grade 1,2 and 3
Exclusion criteria
Exclusion criteria: American Society of Anaesthesiologists 4 and 5 Chronic Obstructive Pulmonary Disease Coronary Artery Disease Liver Dysfunction Renal Dysfunction Cerebrovascular Accidents Increased Intraocular Pressure Patient Refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)CHANGE IN DYNAMIC LUNG COMPLIANCE (C Dyn) 2)CHANGE IN ARTERIAL OXYGENATION (Pao2/FiO2 ratio)Timepoint: 1)AT BASELINE, AT EVERY 60 MINUTE INTERVAL AFTER INITIATION OF PNEUMOPERITONEUM TILL END OF SURGERY 2)ARTERIAL BLOOD GAS SAMPLING AT BASELINE ,AT END OF SURGERY AND POSTOPERATIVE DAY 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Heart rate 2) Mean arterial pressure 3) Oxygen saturation 4) End tidal carbon dioxide 5) Peak inspiratory pressure 6) Plateau pressure 7) Dynamic compliance 8) Static compliance 9) Intra abdominal pressureTimepoint: Each reading will be noted 10 minutes after induction of general anesthesia in supine position, at the end of every hour in trendelenberg and pneumoperitonium and before reversal of general anesthesia in supine position. | — |
Countries
India
Contacts
Rajiv Gandhi Cancer Institute and Research Centre