Health Condition 1: D66- Hereditary factor VIII deficiency
Conditions
Interventions
Intervention1: FACTOR VIII: FACTOR VIII @ 20IU IV STAT TWICE WEEKLY FOR 1 YEAR
Control Intervention1: FACTOR VIII: FACTOR VIII @40 IU IV STAT
ON DEMAND FOR 1 YEAR
Sponsors
DR SAMPURNANAND MEDICAL COLLEGE JODHPUR
Eligibility
Inclusion criteria
Inclusion criteria: DIAGNOSED CASES OF HEMOPHILIA A WHO HAVE HISTORY OF AT LEAST ONE MAJOR BLED NECESSATATING HOSPITALIZATION AND RECIEVING HOSPITALIZED TREATMENT AS PER PROTOCOL
Exclusion criteria
Exclusion criteria: 1) IF A HEMOPHILLIAC CHILD HAS ASSOCIATED BLEEDING TENDENCIES DUE TO LIVER FAILURE, DIC, vWD OR ANTICOAGULANT DRUGS. 2) HEMOPHILLIAC CHILDREN HAVING INHIBITOR. 3) HEMOPHILLIAC CHILDREN WITH COEXISTING DISEASES THAT AFFECT JOINTS SUCH AS OSTEOARTHRITIS , SKELETAL MALFORMATIONS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TO ASSESS THE EFFECTIVENESS OF LOW DOSE PROPHYLACTIC THERAPY IN THE PREVENTION OF BLEEDS AND PRESERVATION OF INDEX JOINT STRUCTURE AS ASSESSED BY JOINT HEALTH SCORE IN ONE YEARTimepoint: TO ASSESS THE EFFECTIVENESS OF LOW DOSE PROPHYLACTIC THERAPY IN THE PREVENTION OF BLEEDS AND PRESERVATION OF INDEX JOINT STRUCTURE AS ASSESSED BY JOINT HEALTH SCORE IN ONE YEAR | — |
Secondary
| Measure | Time frame |
|---|---|
| INCIDENCE OF COMPLICATION , TOTAL COST INCURED , INCIDENCE OF DEVELOPMENT OF INHIBITORTimepoint: ONE YEAR | — |
Countries
India
Contacts
Public ContactDR PRAMOD SHARMA
DR SN MEDICAL COLLEGE JODHPUR
Outcome results
None listed