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The study is done to compare the effect of nalbuphine and clonidine when added to hyperbaric Bupivacaine Intrathecally in lower abdominal and lower limb surgeries

Comparison of Intrathecal Nalbuphine Versus Clonidine as adjuvants to hyperbaric Bupivacaine in Lower abdominal and Lower Limb surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036615
Enrollment
60
Registered
2021-09-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K358- Other and unspecified acute appendicitis

Interventions

Intervention1: Nalbuphine 1.6mg: 3cc of 0.5% hyperbaric bupivacaine with adjuvant nalbuphine 1.6mg in spinal anaesthesia in lower abdominal and lower limb surgeries . Time for study is 18 months. Inte

Sponsors

Dr Simmy John
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II Patients posted for lower abdominal and lower limb surgeries Weight of the patient being in normal range for that age and sex Patients who are not on any antihypertensive, antiplatelet,fibrinolytic or anticoagulant drugs Patients who give informed written consent and are willing to be a part of the study

Exclusion criteria

Exclusion criteria: 1) Patients with pre existing cardiovascular disease ( IHD, hypertension, valvular heart disease), deranged liver functions or renal functions 2) Patients with any Neurological and psychiatric disorders 3) Patients with any contra indication for neuraxial blockade 4) Patients posted for emergency procedures 5) History of allergy to any of the drugs being used under study 6) Unwilling patients

Design outcomes

Primary

MeasureTime frame
â??COMPARISION OF INTRATHECAL NALBUPHINE VS CLONIDINE AS ADJUVANTS TO BUPIVACAINE IN LOWER ABDOMINAL AND LOWER LIMB SURGERIESâ??Timepoint: 0 minute, 1 minute, 2 minutes, 5 minutes, 10 minutes, 15 minutes and 30 minutes—

Secondary

MeasureTime frame
To study and compare changes in various physiological and pharmacological parameters as well as results achieved, when clonidine is used as adjuvant to intrathecal 0.5% Bupivacaine during Spinal anaesthesia for lower abdominal and lower limb surgeries. Timepoint: 0 minute, 1 minute, 2 minutes, 5 minutes, 10 minutes, 15 minutes and 30 minutes—

Countries

India

Contacts

Public ContactDr Simmy John

DR D Y PATIL MEDICAL COLLEGE,PUNE

smitajoshi6@rediffmail.com9995485404

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026