FindTrial
Sign In

comparison of opium free and opium anaesthesia in cancer surgery of head and neck

Opioid free anaesthesia (OFA) vs opioid anaesthesia (OA) in patients undergoing head and neck cancer surgeries: a randomized prospective double blinded study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036580
Enrollment
50
Registered
2021-09-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Control Intervention1: IV lignocaine, IV Dexmedetomidine and IV Ketamine: One group (Group OFA) will receive IV lignocaine 1.5mg/kg, IV Dexmedetomidine 0.5 mcg/kg and IV Ketamine 0.5 mg/kg during indu

Sponsors

DEPARTMENT OF ONCOANAESTHESIA PAIN AND PALLIATIVE CARE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient aged 18-60 years posted for head and neck cancer surgery. 2. Patient belonging to ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Any known allergy to study drugs. 2.Patient with bradycardia(HR 3.Surgeries exceeding > 5hrs. 4. Patients on ventilator in the postoperative period. 5.Patient refusal.

Design outcomes

Primary

MeasureTime frame
To compare the intubation response and propofol requirement in both the groupsTimepoint: During induction and intubation—

Secondary

MeasureTime frame
1.To compare the haemodynamic parameters in both the groups during the intraoperative period. 2.To compare the analgesic consumption in the 24 hr postoperative period. 3.To observe for any side effects in both the groups.Timepoint: Intraoperatively and postoperatively—

Countries

India

Contacts

Public ContactArnav Das

STATE CANCER INSTITUTE

drarundeka25@gmail.com7002833394

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026