Health Condition 1: O- Medical and Surgical Health Condition 2: 8- Other Procedures
Conditions
Interventions
Control Intervention1: Inj Atracurium Besylate: Blood samples will be taken from patients at following times:
i. before induction,
ii.one and two hours after giving first dose of study drug (Inj Atrac
Sponsors
ABVlMS and Dr RML hospital
Eligibility
Inclusion criteria
Inclusion criteria: Consenting adult patients with ASA Grade 1/2 and modified Mallampati grade 1/2
Exclusion criteria
Exclusion criteria: Patients with anticipated difficult airway. Patients with peripheral neuropathy, diabetes mellitus, neuromuscular disorders and myopathies. Patients on antibiotics (e.g., aminoglycosides, tetracyclins, bacitracin, lincomycin, clindamycin, colistin). Patients on drugs like Magnesium sulphate, lithium, procainamide and quinidine. Patients with history of atopy and asthma. Patients with known allergy to any of the drugs involved in study. pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients tryptase levels,IgE levels, absolute eosinophil count, hemodynamic parameters (heart rate and SBP/DBP), cilinical side effects ( flushing of skin, rashes, hypotension, tachycardia, bronchospasm, anaphylaxis, arrhythmias)Timepoint: Blood samples will be taken before induction , one and two hour after giving first dose of study drug and additional sample if and when any side effects occurs. | — |
Secondary
| Measure | Time frame |
|---|---|
| nilTimepoint: nil | — |
Countries
India
Contacts
Public ContactDr Vijay Kumar Nagpal
ABVIMS and Dr RMLH, New Delhi
Outcome results
None listed