Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Intervention1: hfno group: initial flow of oxygen will be 0.25 L/kg body weight and will be increased up to 1 L/kg body weight,Fio2 will be set at 50% and will be titrared according to SpO2 and patien
Sponsors
Deparment Of Anesthesiology And Critical Care
Eligibility
Inclusion criteria
Inclusion criteria: 1.Informed consent from patient or his legal guardian 2.Age between 40 years to 90 years. 3.Known case of COAD
Exclusion criteria
Exclusion criteria: 1.Coexisting hypoxemia (PaO2/FiO2 2.Unconscious patients 3.Those unable to maintain airway because of any neurological reasons 4.Hemodynamically unstable patients 5.Patients with nasal condition affecting the ability to use high frequency nasal cannula-nasal blockage, perforated nasal septum, recent epistaxis etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare changes in partial pressures of Carbon Dioxide between Conventional oxygen therapy (COT)and High Flow Nasal Oxygenation (HFNO) groups.Timepoint: To compare changes in partial pressures of Carbon Dioxide between Conventional oxygen therapy (COT)and High Flow Nasal Oxygenation (HFNO) group at base line ,1 hour and 2 hour | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the changes in i.Partial pressure of oxygen, ii.Incidence of need for mechanical ventilation, iii.Time to discharge from ICU, iv.Time to discharge from hospital, v.Rate of readmission and time to readmission Timepoint: at zero hour .1 hour and 2 hours | — |
Countries
India
Contacts
Public ContactDr Deepak Malviya
dr Ram Manohar Lohiya Institute Of medical sciences
Outcome results
None listed