Health Condition 1: E806- Other disorders of bilirubin metabolism
Conditions
Interventions
None listed
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1) Gestational age more than or equal to 28 to less than 37 weeks, if not ascertainable, then admission weight between more than or equal to 1000 g to less than 2500 g. 2) Neonates with pathologic unconjugated hyperbilirubinemia as per NICE guidelines. 3) Postnatal age 14 days or less.
Exclusion criteria
Exclusion criteria: 1) Neonates who required exchange transfusion prior to and within 24 hours of enrollment. 2) Neonates who have received phototherapy for more than or equal to 6 hours duration prior to enrollment. 3) Neonates with major congenital malformation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of change of total serum bilirubin measured as mg/dl/hour and mg/dl/hour/mg of total serum bilirubin in first 24 ± 4 hours following phototherapy initiation.Timepoint: 15 Days | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of phototherapyTimepoint: 28 Days;Need for exchange transfusionTimepoint: 28 Days;Occurrence of acute bilirubin encephalopathy by M-BIND score.Timepoint: 28 Days;Rate of change in bilirubin albumin molar ratio (BAMR)Timepoint: 15 Days;Rate of change of total serum bilirubin measured as mg/dl/hour and mg/dl/hour/mg of total serum bilirubin until stoppage of phototherapy.Timepoint: 28 Days;Rebound in serum bilirubin at 12 ± 3 hours of discontinuation of phototherapyTimepoint: 28 Days;To evaluate the acceptability of LED intensive phototherapy by mother and staff nurses in pathological unconjugated hyperbilirubinemic unstable preterm neonates.Timepoint: 28 Days | — |
Countries
India
Contacts
Public ContactDr Lalit Kumar
Maulana Azad Medical College Delhi
Outcome results
None listed