A Comparison Study About Does Reduced Sitting Time Improves the Memory Functions and Brain Blood Supply?

Comparison of Effects of Physical Activities of Two Intensities on Vascular and Cognitive Functions

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/09/036496

Enrollment

Registered

2021-09-14

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Doppler Imaging based on the physical activities: The participants will be blinded to the trial randomized the order of activity breaks (uninterrupted sitting, low to moderate group (

2 for MTV

and 3 for control

which will be opened by the participant on the first day of the trial. Familiarized with 4 hours online and offline desk work simulation. Baseline flow velocity, dilatation, and shear stress through d

Eligibility

Inclusion criteria

Inclusion criteria: Participants working in offices (desk-based jobs), Who are willing to practice with the age of 25 â?? 38 years, with low physical activity based on International Physical Activity The questionnaire will be considered for the study and who are willing to participate in the study by signing informed consent.

Exclusion criteria

Exclusion criteria: History of cardiovascular or metabolic disorders, Family history of carotid artery disease and cardiovascular disorders, Persons with psychiatric disorders who are under medication, Bone diseases like Osteomalacia and bone tumor, neuromuscular diseases hindering from adequate activity participation during the study period, drugs altering the vascular function.

Design outcomes

Primary

Measure	Time frame
Doppler ultrasound scan will be performed to determine the Velocity and artery diameter of the Carotid artery and Superficial Femoral Artery. Further, Carotid artery and Superficial Femoral artery endothelial Shear Stress will be measured. A 7 to 15 Â MHz multi-frequency linear array probe attached to a highâ??resolution Doppler machine will be used to note the readings obtained. Timepoint: During the first day of the study i.e., the first week of the trial.	—

Measure

Time frame

Doppler ultrasound scan will be performed to determine the Velocity and artery diameter of the Carotid artery and Superficial Femoral Artery. Further, Carotid artery and Superficial Femoral artery endothelial Shear Stress will be measured. A 7 to 15 Â MHz multi-frequency linear array probe attached to a highâ??resolution Doppler machine will be used to note the readings obtained. Timepoint: During the first day of the study i.e., the first week of the trial.

—

Secondary

Measure	Time frame
By the help of Inquisit licensed software the collected data of Cognitive functions will be measured with Eriksen Flanker tests (Inhibition, reaction time and accuracy for the Flanked and Non flanked stimuli ) N Back memory tests(Working memory, reaction times and accuracy for the stimuli ). Timepoint: The final outcomes will be assessed during the 3rd day of the study. i.e., the third week of the trial of the participants.	—

Measure

Time frame

By the help of Inquisit licensed software the collected data of Cognitive functions will be measured with Eriksen Flanker tests (Inhibition, reaction time and accuracy for the Flanked and Non flanked stimuli ) N Back memory tests(Working memory, reaction times and accuracy for the stimuli ). Timepoint: The final outcomes will be assessed during the 3rd day of the study. i.e., the third week of the trial of the participants.

—

Countries

India

Contacts

Public ContactDr Suresh Sugumar

Manipal College of Health Professions

obhuli.m@learner.manipal.edu9445882423

Outcome results