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Comparison of pain killing effect of incision site injection of 0.75% Ropivacaine( numbing agent) versus blocking the nerves of scalp using 0.75% Ropivacaine in patients undergoing open skull surgeries under general anaesthesia.

Comparison of analgesic effect of incision site infiltration versus scalp nerve block with 0.75% Ropivacaine in cases undergoing supratentorial craniotomy under general anaesthesia: A randomized Interventional study, S.M.S. Medical college, Jaipur during the year 2020-2021.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036479
Enrollment
60
Registered
2021-09-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Scalp Nerve Block: Scalp nerve Block will be given to the patient using 15ml of 0.75% Ropivacaine after induction of anaesthesia Control Intervention1: Incision site infiltration: Incis

Sponsors

Department of Anaesthesiology SMS Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I-III patients willing to give written and informed consent, GCS above 13,Weight of Patients between 40 to 75kg

Exclusion criteria

Exclusion criteria: History of allergy to anaesthetic agents used in the study, History of uncontrolled hypertension, arrhythmia, coagulation disorder, Past History of craniotomy surgery, Pregnancy, Any absolute or relative contraindication to study drug, Non communicative status, Psychiatric patients, Surgery more than 5 hours

Design outcomes

Primary

MeasureTime frame
Mean time duration for the need of first rescue analgesiaTimepoint: After the end of surgery in post operative period—

Secondary

MeasureTime frame
change in intra-operative hemodynamic parametersTimepoint: Baseline, Just after induction, Just after intubation, Just after scalp nerve block/ incision site infiltration, Skin incision, 5 minutes after skin incision, 10 minutes after skin incision, During skull drilling, During dura opening and after every 15 minutes till the end of the surgery;change in mean C-Reactive Protein levelsTimepoint: Baseline, 8hours after skin incision, 24hours after skin incision;percentage of cases who develop side effectsTimepoint: After the end of surgery in postoperative period;Total dose of analgesia requiredTimepoint: 24 hours starting from skin incision—

Countries

India

Contacts

Public ContactDr Vaishali C

SMS Medical College, Jaipur

purohit.shobha@gmail.com7737050823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026