Health Condition 1: F112- Opioid dependence
Conditions
Interventions
Intervention1: Tapentadol: Patients will be give single session of intranasal tapentadol
Control Intervention1: Ketamine: Patients will be given single session of subcutaneous ketamine
Sponsors
GMC RH Patiala
Eligibility
Inclusion criteria
Inclusion criteria: 1.Male and female patients aged 18-65 years with ICD-10 diagnosis of Opioid Dependence. 2.Patients who will bw mdeically stable. 3.Patients who have given written informed consent.
Exclusion criteria
Exclusion criteria: 1. History of chronic psychosis or drug induced psychosis of any kind. 2. Patients with paralytic ileus and respiratory depression. 3. Pregnant women, lactating mothers, surgically-sterile women or women who agree to continue using applicable birth control throughout the trial. All women of child-bearing potential must have a negative urine pregnancy test. 4. History of seizures, renal insufficiency or congestive heart failure. 5. History of ketamine abuse/dependence or prior clinically significant adverse reaction to ketamine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome will be improvement on the BPI (Brief Pain Inventory scale)Timepoint: Patients will be assessed at baseline ,2hrs,3hrs, 6hrs, 24hrs, 48hrs, 72hrs. | — |
Secondary
| Measure | Time frame |
|---|---|
| ADRTimepoint: After every session | — |
Countries
India
Contacts
Public ContactDr Ramanpreet Kaur
Department of Psychiatry
Outcome results
None listed