Comparison of pain, pain medicine requirement and in patients undergoing spine surgeries.

Comparison of postoperative pain, perioperative analgesia consumption and surgical stress in patients receiving Erector spinae plane block versus conventional analgesia for spine surgeries

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/09/036430

Enrollment

200

Registered

2021-09-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: ERECTOR SPINAE BLOCK WITH 0.25% BUPIVACAINE: ESP block will be performed in prone position after general anaesthesia is administered but before start of surgery. ESP block will be perfo

Eligibility

Inclusion criteria

Inclusion criteria: Age â?? 18 to 65 years, Either gender, ASA grade I to III, Elective spine surgeries in prone position involving up to 4 vertebral levels and lasting up to 6 hours

Exclusion criteria

Exclusion criteria: Surgeries involving C1 and C2 levels, Spine tumors requiring TIVA and neuromonitoring, Any contraindications to regional block such as local infections or allergy to local anesthetics, Refusal of consent

Design outcomes

Primary

Measure	Time frame
To compare the intraoperative opioid consumption and acute postoperative pain (up to 48hours) in patients undergoing spine surgeries with and without ESP blockTimepoint: 48hours	—

Secondary

Measure	Time frame
Measures of nociception between the 2 groups using Surgical Pleth Index, and systemic hemodynamics (heart rate and mean blood pressure)Timepoint: every 15min during the surgery;To assess surgical stress between the 2 groups using Biomarkers (cortisol, glucose, leucocytes count)Timepoint: Immediately before and after surgery;To compare adverse events related to analgesia techniques till 48 h after surgery [Pruritus, urinary retention, PONV, delayed recovery from anaesthesia, etc. related to opioid and hypotension, pneumothorax related to ESP block]Timepoint: upto 48 hours after surgery;To compare chronic pain between 2 groups at 3 months after surgery by telephonic interview [intensity, need and response to analgesics and effect of pain on quality of life and return to work]Timepoint: at 3months after surgery;To compare quality of sleep between the two groups using Likert sleep scaleTimepoint: On postoperative day 1 and day 2;To compare rescue analgesic requirements between the 2 groups postoperativelyTimepoint: Up to 48 h after surgery	—

Measure

Time frame

Measures of nociception between the 2 groups using Surgical Pleth Index, and systemic hemodynamics (heart rate and mean blood pressure)Timepoint: every 15min during the surgery;To assess surgical stress between the 2 groups using Biomarkers (cortisol, glucose, leucocytes count)Timepoint: Immediately before and after surgery;To compare adverse events related to analgesia techniques till 48 h after surgery [Pruritus, urinary retention, PONV, delayed recovery from anaesthesia, etc. related to opioid and hypotension, pneumothorax related to ESP block]Timepoint: upto 48 hours after surgery;To compare chronic pain between 2 groups at 3 months after surgery by telephonic interview [intensity, need and response to analgesics and effect of pain on quality of life and return to work]Timepoint: at 3months after surgery;To compare quality of sleep between the two groups using Likert sleep scaleTimepoint: On postoperative day 1 and day 2;To compare rescue analgesic requirements between the 2 groups postoperativelyTimepoint: Up to 48 h after surgery

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Countries

India

Contacts

Public ContactDr M Mahendranath

NIMHANS

drsri23@rediffmail.com9481445949

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026