Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Control Intervention1: Intravenous Atracurium: Intravenous Atracurium 0.5mg/kg loading dose followed by 0.15mg/kg maintenance with regards to potency, onset time of neuromuscular blockade and recovery
Sponsors
Dheeraj Gopal Ravindran
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I or II fit patients. 2. Patients aged between 18 and 60 years of age. 3. Patients undergoing surgeries under general anaesthesia. 4. Haemodynamically stable patients with all routine investigations within normal limits and without any comorbidities. 5. Written informed consent from the concerned patient.
Exclusion criteria
Exclusion criteria: 1. Patients who are not willing to participate in the study. 2. Patients with ASA grade III and above physical status. 3. Patients who are aged less than 18 and more than 60 years of age. 4. Patients who are posted for emergency procedures. 5. Patients with known allergy to the study drugs. 6. Patients with difficult intubation. 7. Patients who are obese. 8. Patients who have psychiatric, neurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To compare onset time for intubation. 2. To observe intubating conditions. 3. To compare duration of neuromuscular blockade.Timepoint: Time taken from administration of study drug to intubation in seconds and the duration of neuromuscular blockade in minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To observe hemodynamic effects of both drugs. 2. To observe any side effects.Timepoint: Hemodynamic parameters recorded before induction, after giving study drug, at the time of intubation and at 1, 2, 3, 5, 10 and 15 min after intubation | — |
Countries
India
Contacts
Public ContactDheeraj Gopal Ravindran
Dr. D. Y. Patil Medical College, Hospital & Research Centre
Outcome results
None listed