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Treatment of permanent teeth with dead pulp by a technique to renew pulp to regain natural defence mechanism for pulp.

A comparative evaluation of PRF, platelet pellet and collagen as scaffolds in Regenerative Endodontic therapy in Permanent mature teeth with necrotic pulp and apical periodontitis. - RCT

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036395
Enrollment
24
Registered
2021-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: A comparative evaluation of PRF, platelet pellet and collagen as scaffolds in Regenerative Endodontic therapy in Permanent mature teeth with necrotic pulp and apical periodontitis.: An

Sponsors

Dr Supriya Gupta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Asymptomatic Patients with necrotic pulp in permanent mature teeth with a closed apex associated with or without periapical radiolucency, no response of vital pulp with thermal test and electric pulp testing, no tooth mobility, and a pocket depth <3 mm.

Exclusion criteria

Exclusion criteria: Patients with medical conditions like cardiac problems, pregnant patients, diabetic patients, bleeding tendencies, HIV+ patients, hepatitis-B. All patients will go through HIV screening.

Design outcomes

Primary

MeasureTime frame
Elimination of symptoms and evidence of bone healing.Timepoint: 3 Months, 6 months, 9months, 12 months

Secondary

MeasureTime frame
positive response to pulp vitality testingTimepoint: 3 Months, 6 months, 9months, 12 months

Countries

India

Contacts

Public ContactDr Neelam Mittal

Banaras Hindu University

dr.neelammittal@gmail.com9415203360

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026