Skip to content

Comparative study between Noradrenaline and Ephedrine to treat hypotension during spinal anesthesia for C- section

A prospective randomized double blind comparative study to determine the efficacy of Norepinephrine versus Ephedrine to maintain arterial blood pressure during spinal anaesthesia for Cesarean delivery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036361
Enrollment
110
Registered
2021-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ephedrine or norepinephrine to prevent and treat spinal anaesthesia induced hypotension: Ephedrine 10 mg or noradrenaline 6mcg bolus prophylactic just after Anaesthesia and 10 mg bolus

Sponsors

Karnataka Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-50 years parturient with singleton pregnancy undergoing elective cesarean sections ï?· American Society of Anesthesiologist (ASA)physical status:1 and 2. ï?· Informed, written and valid consent by patients and their guardians .

Exclusion criteria

Exclusion criteria: 1.Parturient with allergy or hypersensitivity to ephedrine or norepinephrine 2.Height 180cm ,BMI >40kg/m2 3.any hypertensive disorders of pregnancy, 4.parturient with cardiovascular disease 5.parturient with cerebrovascular disease 6.fetal abnormalities

Design outcomes

Primary

MeasureTime frame
Number of boluses of pressor used during Cesarean sectionTimepoint: From time of induction -first minute, then every 3 minute once for 10 minutes and then every 5 minute intervals till time of complete skin closure

Secondary

MeasureTime frame
Incidences of Hypotension,bradycardia,tachycardia,reactive hypertension IVF infused intraop Time taken from incision to delivery of baby Total duration of surgery will be noted Incidences of nausea ,vomiting or dizziness due to hypotension Fetal outcome APGARTimepoint: First minute post induction ,then every 3 minutes for 10 minutes and then at every 5 minutes intervals till complete skin closure

Countries

India

Contacts

Public ContactSwaroop Rani R

karnataka institute of medical sciences hubli

dr.sushsam@gmail.com9844310403

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026