Health Condition 1: S069- Unspecified intracranial injury
Conditions
Interventions
Intervention1: Painful and auditory stimulus: Painful stimulus in the form of sustained pressure for around 5 seconds at the fingernail bed and auditory stimulus in the form of clapping twice near pat
Sponsors
National institute of Mental health and Neurosciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients 18 years and above with acute traumatic brain injury with Glasgow coma scale motor response <=4 anytime between day3-5 of injury
Exclusion criteria
Exclusion criteria: 1.Patients with extracranial injuries 2.Haemodynamically unstable patients 3.Patient in ictal or post ictal state 4.Severe sodium disturbances (serum sodium 160 meq/L) 5.Severe glucose disturbances (blood glucose 300 mg/dl 6.Patients in severe sepsis 7.Patient refusal 8.Patients who become conscious (e.g, BIS >80 or 95%SEF >25) at the time of application of painful stimulus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the incidence of EEG-R and BIS-R to painful and auditory stimuli in unconscious patients with acute severe traumatic brain injury and its correlation with the outcome assessed by GOSETimepoint: Discharge, 3rd and 6th month after injury | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. To evaluate association between EEG & BIS parameters with patientâ??s demographic and clinical detailsTimepoint: Discharge, 3rd and 6th month after injury;To study combination of various EEG parameters (such as burst suppression ratio, average amplitude, spectral edge frequency, peak power frequency, band ratios) and BIS in prediction of patientâ??s outcomeTimepoint: Discharge, 3rd and 6th month after injury;To study interrater agreement of EEG and BIS parametersTimepoint: Discharge, 3rd and 6th month after injury | — |
Countries
India
Contacts
Public ContactDr Gayatri Sakrikar
National Institute of Mental Health & Neurosciences
Outcome results
None listed