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Preoperative Sugar Containing Fluid Reduces Post Operative Nausea and Vomiting

The Effect Of Dextrose Infusion On Incidence Of Postoperative Nausea And Vomiting And its Correlation With Plasma Osmolarity On Patients Undergoing Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036331
Enrollment
150
Registered
2021-09-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 5% Dextrose infusion: One litre of fluid contains Glucose 50 grams. Control Intervention1: Ringer Lactate infusion: One litre of fluid supplies Sodium 130 mEq, Calcium 3 mEq, Potassium

Sponsors

Bankura Sammilani Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18-50 years of both sex. 2. Patients scheduled for elective laparoscopic cholecystectomy under general anaesthesia. 3. Patients with ASA grade 1 and 2. 4. Mallampati grading 1 and 2.

Exclusion criteria

Exclusion criteria: 1. Unwilling patients. 2. Emergency surgeries. 3. Anticipated difficult intubation. 4. Diabetic patients. 5. Pregnant & lactating females. 6. Patients with chronic opioid use. 7. Patients with vertigo & migraine. 8. Patients with behavioral disorder.

Design outcomes

Primary

MeasureTime frame
Through our designed study we expect to stand out dextrose containing IV fluid as a simple inexpensive, safe method for prophylaxis of PONV after laparoscopic cholecystectomyTimepoint: Postoperatively up-to 4 hour—

Secondary

MeasureTime frame
To find out effect of dextrose solution on plasma osmolarity and any correlation between plasma osmolarity and postoperative nausea and vomiting.Timepoint: Postoperatively up-to 4 hour—

Countries

India

Contacts

Public ContactAYAN PATRA

Bankura Sammilani Medical College & Hospital

dr.subratapahari@yahoo.com8617012667

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026