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The effect of combining Lidocaine with Dexamethasone for attenuating postoperative sore throat, cough and hoarseness

Effect of lignocaine on post-operative sore throat as an adjuvant to dexamathasone in lower abdominal surgeries under general anaesthesia : A randomized, double blind, controlled, intervententional study at SMS Hospital during 2020 - 2021

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036312
Enrollment
74
Registered
2021-09-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: inj. lignocaine: inj. lignocaine 1.5mg/kg in 10 ml of saline given intravenously at the time of induction check for post-operative sore throat at 1 and 24 hrs Control Intervention1: inj

Sponsors

SMS Medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA grade I and II Non smoker Duration of surgery >1 hr. Informed and written consent

Exclusion criteria

Exclusion criteria: Patients with preoperative sore throat, cough and hoarseness H/o respiratory infection within last 2 week Allergy to study drugs Preoperative treatment with corticosteroids Patient with Mallampati grade III and IV More than one attempt for orotracheal intubation

Design outcomes

Primary

MeasureTime frame
To determine the difference in percentage of cases who developed sore throat at 1 hour and 24 hours post-operative period in both the groups.Timepoint: 1hr and 24 hrs—

Secondary

MeasureTime frame
Determine the difference in cases who developed symptoms in both the groupsTimepoint: One day—

Countries

India

Contacts

Public ContactDr Ankit Saini

Sawai mann singh medical college and hospital

drmamtakhandelwal@gmail.com9929338174

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026