None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Individuals with good general health and age between 18-60 years. 2. Subjects who have not received periodontal therapy, in the previous six months. 3. Subjects who readily give informed consent for the study. 4. Systemically healthy patients .
Exclusion criteria
Exclusion criteria: 1. Consumption of tobacco in any form and alcoholics. 2. Pregnant and lactating females. 3. Subjects who have received anti-inflammatory, antibiotic and steroid drugs in previous three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a) To determine the level of Sirtuin-1 in serum of periodontally healthy patients. b) To determine the level of Sirtuin-1 in serum of chronic periodontitis patients. c) To compare the levels of Sirtuin-1 in serum of periodontally healthy and chronic periodontitis patients. d) To compare the serum levels of Sirtuin-1 before and after scaling and root planing in chronic periodontitis patients.Timepoint: Baseline 4 weeks after scaling and root planing | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate improvement in plaque index, gingival index,pocket probing depth and clinical attachment level in patients with chronic periodontitis 4 weeks after scaling and root planing.Timepoint: Plaque index, gingival index, pocket probing depth and clinical attachment level in patients with chronic periodontitis will be taken at baseline and then 4 weeks after scaling and root planing | — |
Countries
India
Contacts
Terna Dental College and Hospital