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A study of the comparative effect of two drugs on the depth of anaesthesia.

To study the sevoflurane sparing effect of dexmedetomidine infusion on entropy level in abdominal laparoscopic procedure: RCT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036286
Enrollment
30
Registered
2021-09-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K400- Bilateral inguinal hernia, with obstruction, without gangrene Health Condition 2: K801- Calculus of gallbladder with othercholecystitis Health Condition 3: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 4: N971- Female infertility of tubal origin Health Condition 5: K358- Other and unspecified acute appendicitis Health Condition 6: N29- Other disorders of kidney and ureter in diseases classified elsewhere Healt

Interventions

Intervention1: Dexmedetomidine adjuvant with sevoflurane: Sevoflurane sparing effect of dexmedetomidine infusion on entropy level monitoring in abdominal laparoscopic surgery 1mcg/kg bolus followed b

Sponsors

AFMC Pune
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASAI&II Elective surgery Laparoscopic surgery Duration up to 4 hrs

Exclusion criteria

Exclusion criteria: ASA III&IV Previously diagnosed cardiac renal and hepatic disorder Open abdominal surgery

Design outcomes

Primary

MeasureTime frame
To study the concentration of sevoflurane requirement for maintenance of anaesthesia when used with dexmedetomidine using entropy To study the concentration of sevoflurane required to maintain adequate depth of anaesthesia using entropy when used with placebo.Timepoint: Every 10 min From Time of induction Till extubation time of surgery. Approx 4 hrs..

Secondary

MeasureTime frame
To study the entropy level of dexmedetomidine infusion over haemodynamic changes.Timepoint: From intubation to extubation

Countries

India

Contacts

Public ContactDr Rangraj Setlur

AFMC pune

Rangraj@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026