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LOCAL INTRAWOUND VANCOMYCIN ANTIBIOTIC POWDER APPLICATION IN ADDITION TO INTRAVENOUS ANTIBIOTICS ON POSTOPERATIVE INFECTION IN ORTHOPAEDIC SURGERIES

A RANDOMIZED CONTROL TRIAL TO DETECT THE EFFICACY OF USING INTRAVENOUS ANTIBIOTIC ONLY VERSUS LOCAL INTRAWOUND VANCOMYCIN ANTIBIOTIC POWDER APPLICATION IN ADDITION TO INTRAVENOUS ANTIBIOTICS ON POSTOPERATIVE INFECTION IN ORTHOPAEDIC SURGERIES

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036275
Enrollment
200
Registered
2021-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified

Interventions

Intervention1: LOCAL INTRAWOUND VANCOMYCIN ANTIBIOTIC POWDER: Our study will include the intrawound application of vancomycin powder(2gm,4gm) intraoperatively before wound closure along preoperative a

Sponsors

Government Medical College and Rajindra hospital Patiala
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients above the age of 18 years being admitted under department of orthopaedics, GMC Patiala for operative procedures. 2. All operative procedures being carried out in the department of orthopaedics, GMC Patiala.

Exclusion criteria

Exclusion criteria: 1. Patients allergic to vancomycin. 2. Patients undergoing minimally invasive procedures.

Design outcomes

Primary

MeasureTime frame
To assess the efficacy of local vancomycin powder in controlling postoperative infection in orthopaedic surgeries.Timepoint: Post op assessment based on : Pre and post operative hemoglobin, TLC , DLC, ESR, CRP(quantitative),estimated blood loss, RBS Wound cultures to be collected, if indicated. Wound assessment on Post operative days 5, 8, 12. Final wound assessment on day 30. Follow up till 12 weeks.—

Secondary

MeasureTime frame
To bring about a change in the treatment modality in order to reduce surgical site infections. To assess the incidence of SSI in both the groups. To assess the duration of various surgeries, patient demographics, comorbidities, estimated blood loss, complete blood count. Timepoint: Post op assessment based on : Pre and post operative hemoglobin, TLC , DLC, ESR, CRP(quantitative),estimated blood loss, RBS Wound cultures to be collected, if indicated. Wound assessment on Post operative days 5, 8, 12. Final wound assessment on day 30. Follow up till 12 weeks.—

Countries

India

Contacts

Public ContactDr Gurnik Singh

Government Medical College and Rajindra hospital Patiala

singhgurnik@gmail.com8968321811

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026