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Use of a drug for prevention of spinal induced hypotension in old age patients.

Prophylactic Use of Intramuscular Mephenteramine For Prevention of Spinal Induced Hypotension In Elderly Patients Undergoing Hip Fracture Surgery: A Randomised Placebo Controlled Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036268
Enrollment
130
Registered
2021-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S720- Fracture of head and neck of femur Health Condition 2: M169- Osteoarthritis of hip, unspecified Health Condition 3: M808- Other osteoporosis with current pathological fracture Health Condition 4: M165- Unilateral post-traumatic osteoarthritis of hip Health Condition 5: S799- Unspecified injury of hip and thigh Health Condition 6: S799- Unspecified injury of hip and thigh

Interventions

Intervention1: Intramuscular injection of Mephenteramine for prevention of spinal induced hypotension: 30 mg injection Mephenteramine intramsucularly just after spinal anaesthesia. Control Interventi

Sponsors

MAHARANA BHUPAL GOVT HOSPITALUDAIPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age >60 years undergoing surgery for hip fracture

Exclusion criteria

Exclusion criteria: 1.Patient Refusal 2.Morbid Obesity 3.Contraindication to subarachnoid block 4.Coexisting severe medical illness like severe respiratory disease(SpO2 160/100) 5.Neurological Disease (Stroke,Alzheimer,Paralysis) 6.Psychiatric Disease,uncontrolled endocrine disorder 7.Coagulation abnormalities

Design outcomes

Primary

MeasureTime frame
Hemodynamic stability Incidence of Hypotension requiring treatmentTimepoint: intraoperatively(120 minutes after spinal anaesthesia)—

Secondary

MeasureTime frame
Vasopressor Requirement Side effectsTimepoint: postoperatively(upto 24 hours)—

Countries

India

Contacts

Public ContactDr Ansika Yadav

RNT Medical College,Udaipur,

uditanaithani@gmail.com9829414752

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026