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The better method for pain relief in children undergoing surgeries in lower abdomen, genital region or legs.

Effect of intravenous dexmedetomidine in combination with caudal analgesia on postoperative pain control in children undergoing lower abdominal or perineal surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036260
Enrollment
64
Registered
2021-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous dexmedetomidine along with caudal analgesia (Group D).: Children will receive caudal block analgesia with 1 mL/kg of 0.25% bupivacaine and 1mcg/kg dexmedetomidine intraven

Sponsors

Department of Anaesthesiology and Critical Care Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Physical status ASA (American Society of Anaesthesiologists) I-II. 2. Age of patient 2-8 years

Exclusion criteria

Exclusion criteria: 1. Skin infection at the site of caudal block 2. Thrombocytopenia or bleeding disorders or coagulopathy 3. History of hypersensitivity to local anaesthetics 4. Neuromuscular disease 5. Spinal deformity 6. Cerebral palsy and mental retardation

Design outcomes

Primary

MeasureTime frame
The time to first rescue analgesic requirementTimepoint: May differ in each patient; in the postoperative period.

Secondary

MeasureTime frame
Duration of motor blockadeTimepoint: May differ in each patient; in the postoperative period.;End tidal sevoflurane concentration required for the target BIS scoreTimepoint: Throughout intraoperative period;Incidence of side effects- emergence agitation (EA), hypotension, bradycardia, respiratory suppression, nausea, vomiting, motor weakness, and urinary retentionTimepoint: Intraoperative and postoperative period till 24 hours.;Number of patients not requiring rescue analgesia over first 24 hours postoperativelyTimepoint: 24 hours;Postoperative behaviour scoresTimepoint: 0, 15, 30, 60, 90 and 120 minutes;Postoperative pain scoreTimepoint: 0, 8, 12 and 24 hours

Countries

India

Contacts

Public ContactHimanshee Rathi

Lok Nayak Hospital

ucverma2k@gmail.com7838976768

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026