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Inflammatory markers for prognosis of sepsis and septic shock

A qualitative evaluation of procalcitonin (PCT), Creactive protein (CRP) and interleukin-6 (IL-6) for prognosis of sepsis & septic shock.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/09/036242
Enrollment
300
Registered
2021-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

None listed

Sponsors

Dr B L Kapur Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients admitted in Medical ICU with a suspected diagnosis of Sepsis and Septic Shock, with likely stay >72 hours.

Exclusion criteria

Exclusion criteria: 1.Patients undergoing any emergency surgery. 2. Patients with a diagnosis of cancer or undergoing therapy for cancer. 3. Pregnant patients 4. Extremely critical patients: Refractory shock, Severe refractory metabolic acidosis (pH or more organ failures on presentation), APACHE II >35, SOFA >20.

Design outcomes

Primary

MeasureTime frame
Prognostic value of Procalcitonin (PCT), C-Reactive Protein (CRP) and Interleukin-6 (IL-6) in patients with sepsis and septic shockTimepoint: Day 1,Day 3,Day 7 and day 12

Secondary

MeasureTime frame
To assess correlation Procalcitonin (PCT), C-Reactive Protein (CRP) and Interleukin-6 (IL-6) with disease severity scoring systems- Acute Physiology & Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment score (SOFA).Timepoint: The APACHE II score will be collected once only after 24-hour of admission to ICU. SOFA scores of Day1, 3, 7 and 12 will be taken into consideration.

Countries

India

Contacts

Public ContactDr Vishal Upadhyay

BLK-MAX Super Speciality Hospital

drpbag@gmail.com9999879975

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026