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DEXMEDETOMIDINE ON POSTOPERATIVE NEUROMUSCULAR RECOVERY IN SPINAL SURGERY

STUDY OF EFFECTS OF DEXMEDETOMIDINE ON POSTOPERATIVE NEUROMUSCULAR RECOVERY IN SPINAL SURGERY

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036221
Enrollment
64
Registered
2021-09-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: M488- Other specified spondylopathies Health Condition 3: M489- Spondylopathy, unspecified

Interventions

Intervention1: Dexmedetomidine: Postoperative neuromuscular recovery and changes in hemodynamic parameter after premedication and intra operative dexmedetomidine infusion Control Intervention1: 0.9% N

Sponsors

JAWAHARLAL NEHRU MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I & II patients of either sex. Mallampatti grades I & II. Patients planned for elective surgery.

Exclusion criteria

Exclusion criteria: Patients with cardiovascular disease like coronary artery disease, hypertension, etc. Pulmonary disease like asthma, COPD, cor-pulmonale. Patients with neuro-muscular, hepatic or major renal disease. Patients with anticipated difficult intubation, potentially full stomach patients (trauma, morbid obesity, pregnancy) and diabetes mellitus. History of alcohol or drug abuse. History suggestive of hiatus hernia/GERD.

Design outcomes

Primary

MeasureTime frame
Time to achieve neuromuscular recovery, in term of TOFR â?¥ 70% and also â?¥90% after administration of reversal agent.Timepoint: 5 minute after administration of reversal agent 15 minute after administration of reversal agent 30 minute after administration of reversal agent 60 minute after administration of reversal agent

Secondary

MeasureTime frame
Time to achieve Modified Aldrete Score 9 or 10 To assess Ramsay Sedation Score To assess Patients Satisfaction Score Timepoint: 5 minute after administration of reversal agent 15 minute after administration of reversal agent 30 minute after administration of reversal agent 60 minute after administration of reversal agent

Countries

India

Contacts

Public ContactShahla Haleem

Department Of Anaesthesiology And Critical Care, JNMCH, AMU, Aligarh, UP, India, 202002

shahlahaleem@yahoo.co.in9997448172

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026