Health Condition 1: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
None listed
Sponsors
ALL INDIA INSTITUTE OF MEDICAL SCIENCES RAIPUR
Eligibility
Inclusion criteria
Inclusion criteria: 1. Either gender diagnosed with Type 2 Diabetic Mellitus. 2. 18-75 years of age. 3. Uncontrolled blood glucose level in spite of exercise dietary goals plus on metformin monotherapy. 4. Treatment naïve patient with HbA1c
Exclusion criteria
Exclusion criteria: 1. Type 1 Diabetes mellitus. 2. Pregnant & lactating women. 3. Type 2 Diabetic Mellitus patients on insulin or on OADs other than metformin and sulphonylureas. 4. Patients with HbA1c 10%. 5. Patients who are allergic to drugs containing sulfa component in their chemical structure. 6. Patients who are suffering with end stage systemic diseases. 7. Patients in Intensive Care Unit (ICU).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in glycated hemoglobin (HbA1c) level in individuals with polymorphism of ATP sensitive potassium channels after 12 weeks treatment with sulphonylureas.Timepoint: 12 MONTHS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change in HbA1c level in individuals with polymorphism in ATP sensitive potassium channels after 24 weeks treatment with sulfonylureas. 2. Change in fasting blood glucose and C-peptide level in patients after 1 week of sulfonylurea therapy. 3. Prevalence of various polymorphisms in Type 2 Diabetic Mellitus patients in the Chhattisgarh Population 4. To test the association of various polymorphisms and their insulin release and insulin resistance at baseline and 12 weeks of therapy. Timepoint: 12 MONTHS | — |
Countries
India
Contacts
Public ContactPUGAZHENTHAN T
ALL INDIA INSTITUTE OF MEDICAL SCIENCES (AIIMS)
Outcome results
None listed