Health Condition 1: C069- Malignant neoplasm of mouth, unspecified
Conditions
Interventions
Intervention1: Dextran 40 infusion at 30ml/hour for 72 hours post operatively: Patients will be given test dose of Dextran-40 20 ml intraoperataively to check for anaphylactic reactions. If tolerating
Sponsors
Dr Zaid Shaikh
Eligibility
Inclusion criteria
Inclusion criteria: Biopsy proven patients with oral cavity malignancy, planned for surgical treatment and requiring reconstruction with pedicled flap will be included.
Exclusion criteria
Exclusion criteria: Age of the patients 70 years, patients with hemodynamic compromise, patient with history of previous cardiac or pulmonary complications like PAH, Pulmonary edema, Coronary artery disease with history of interventions.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic parametersTimepoint: On POD 1 and before discharge;Post operative chest X-ray compared with pre-operative chest X-RayTimepoint: On post operative day 1;Post operative neck drain to be measured. If chest drain insitu that too has to be measured on every post operative dayTimepoint: On post operative day 1,2,3,4,5 until drain removal | — |
Primary
| Measure | Time frame |
|---|---|
| Flap survival status post operatively to be assessed and compared with intraoperative pictureTimepoint: Flap survival status post operatively will be assessed on POD1,3,5 and 7 | — |
Countries
India
Contacts
Public ContactDr Dillip Samal
AIIMS Bhubaneswar
Outcome results
None listed