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Clinico-radiographic study to compare and evaluate the efficacy of Demineralized Freeze-Dried Bone Allograft (DFDBA) with and without Concentrated Growth Factors Membrane (CGFM) in the treatment of periodontal defects.

Comparative evaluation of Demineralized Freeze-Dried Bone Allograft with and without Concentrated Growth Factors Membrane in the treatment of periodontal intrabony defects: A clinico-radiographic study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036126
Enrollment
60
Registered
2021-09-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Demineralized Freeze-Dried Bone Allograft: The trial is an Interventional study in which efficacy of Demineralized Freeze-Dried Bone Allograft with and without Concentrated Growth Facto

Sponsors

Self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients with age group 30 to 50 years. 2 Patients with severe periodontitis as assessed by probing pocket depth (PPD) >= 5mm and clinical attachment level (CAL) >= 4mm exhibiting bilateral intrabony defects. 3 Patients with no systemic diseases.

Exclusion criteria

Exclusion criteria: 1 Patients with history of systemic diseases, allergies or drug usage. 2 Patients who have undergone periodontal treatment in previous 6 months. 3 Pregnant and lactating females.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the efficacy of DFDBA alone and in combination with CGFM in the treatment of periodontal intrabony defects, clinically and radiographically by CBCT.Timepoint: Baseline and 18 months—

Secondary

MeasureTime frame
OTHER OBJECTIVE 1 To evaluate and compare the changes between the groups in Clinical attachment level and Periodontal pocket defect at baseline 3 months and 6 months. OTHER OBJECTIVE 2 To evaluate Bone Defect height, Bone defect width, Bone defect depth, and Bone defect volume at baseline and at 6 months radiographically using CBCT. Timepoint: 18 months—

Countries

India

Contacts

Public ContactDr Abhay Kolte

V.S.P.M Dental College & Research Centre, Digdoh Hills, Hingna Road, Nagpur

drabhaypkolte@gmail.com9011071467

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026