FindTrial
Sign In

Effect of dexmedetomidine on eye and venous pressure in patients undergoing elective neurosurgical procedure.

To evaluate the effect of dexmedetomidine as an anaesthetic adjuvant on optic nerve sheath diameter (ONSD) and central venous pressure (CVP) in patients undergoing elective neurosurgical procedures.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/09/036111
Enrollment
40
Registered
2021-09-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine alone: Dexmetedomidine IV bolus in a dose of 0.5 mcg/kg before start of anesthesia and continued as infusion in the dose of 0.2 mcg/ kg /hr until the start of skin closu

Sponsors

Department of anaesthesiology and critical care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Written informed consent ASA 1 and 2 Age - 15 - 60 years Gender -male and female Patients with elective neurosurgical procedures.

Exclusion criteria

Exclusion criteria: No extended intracranial pressure but increased optic nerve diameter. Optic nerve disease such as optic neuritis , Arachnoid cyst of optic nerve. Anterior orbital or cavernous sinus mass. Known orbital injury or prior ocular surgery. Histroy of allergy to alpha 2 agonists.

Design outcomes

Primary

MeasureTime frame
To assess the effect of dexmedetomidine as an anaesthetic adjuvant on optic nerve sheath diameter (ONSD) in adult patients. To assess the effect of dexmedetomidine as an anaesthetic adjuvant on central venous pressure (CVP) in adult patients undergoing elective neurosurgical procedures.Timepoint: 10 months—

Secondary

MeasureTime frame
To find the correlation between ONSD and CVP in adult patients undergoing elective neurosurgical procedures. Documentation of side effects -nausea , vomiting , hypotension, bradycardia,during and after surgery.Timepoint: 10 months—

Countries

India

Contacts

Public ContactKarishma

Department of anesthesiology and critical care , Jawaharlal Nehru Medical College and hospital

shahlahaleem@yahoo.co.in9997448172

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026